Hsd11b1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comHsd11b1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Hsd11b1(Gene name) > Rat

Hsd11b1 (Gene name),

Corticosteroid 11-beta-dehydrogenase isozyme 1 (Protein name ), DHI1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Hsd11b1(Hsd11);

Protein name:

Corticosteroid 11-beta-dehydrogenase isozyme 1;

Alternative:

11-beta-hydroxysteroid dehydrogenase 1(11-DH;11-beta-HSD1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homodimer.

Function:

Catalyzes reversibly the conversion of corticosterone to 11-dehydrocorticosterone.

Subcellular Location:

Endoplasmic reticulum membrane Single-pass type II membrane protein

Protein Attributes:

Sequence length:

288

Sequence:

50:

100:

150:

200:

250:

288:

EVYYDKSSWT | PLLLGNPGRR | IMEFLSLRSY | NRDLFVSN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.185798

Pfam:

PF00106

SMR:

P16232

UniGene:

Rn.231830

String:

P16232

KEGG:

rno:25116

Uniprot:

P16232

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ELISA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

E2268h

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96T

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ELISA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

E2268r

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ELISA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

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ELISA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

E2268m

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Packing:

96T

CLIA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

U2268m

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MSDS:

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Packing:

96T

CLIA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

U2268r

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MSDS:

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Packing:

96T

CLIA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

U2268h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

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Polyclonal Antibody for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

P2268Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

P2268Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Cat.:

P2268Rb-r

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

Protein for Rat Corticosteroid 11-beta-dehydrogenase isozyme 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Cloning and expression of rat cDNA encoding corticosteroid 11 beta-dehydrogenase."
Agarwal A.K. , Monder C. , Eckstein B. , White P.C.
J. Biol. Chem.264:18939-18943(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 11-HSD1A)
tissue: Liver.
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Kidney.
3.

"Differential promoter usage by the rat 11 beta-hydroxysteroid dehydrogenase gene."
Moisan M.P. , Edwards C.R. , Seckl J.R.
Mol. Endocrinol.6:1082-1087(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 1-69 (ISOFORMS 11-HSD1A AND 11-HSD1B);ALTERNATIVE PROMOTER USAGE
4.

"C/EBP regulates hepatic transcription of 11beta-hydroxysteroid dehydrogenase type 1. A novel mechanism for cross-talk between the C/EBP and glucocorticoid signaling pathways."
Williams L.J.S. , Lyons V. , MacLeod I. , Rajan V. , Darlington G.J. , Poli V. , Seckl J.R. , Chapman K.E.
J. Biol. Chem.275:30232-30239(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-69 (ISOFORM 11-HSD1A)
strain: Sprague-Dawley.
5.

"Purification of full-length recombinant human and rat type 1 11beta-hydroxysteroid dehydrogenases with retained oxidoreductase activities."
Nobel C.S.I. , Dunas F. , Abrahmsen L.B.
Protein Expr. Purif.26:349-356(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE OF 21-273
6.

"Tissue-specific expression of an 11 beta-hydroxysteroid dehydrogenase with a truncated N-terminal domain. A potential mechanism for differential intracellular localization within mineralocorticoid target cells."
Krozowski Z. , Obeyesekere V. , Smith R. , Mercer W.
J. Biol. Chem.267:2569-2574(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 11-HSD1A AND 11-HSD1B);ALTERNATIVE PROMOTER USAGE
strain: Sprague-Dawley.
tissue: Kidney.
7.

"The syndrome of apparent mineralocorticoid excess: its association with 11 beta-dehydrogenase and 5 beta-reductase deficiency and some consequences for corticosteroid metabolism."
Monder C. , Shackleton C.H.L. , Bradlow H.L. , New M.I. , Stoner E. , Iohan F. , Lakshmi V.
J. Clin. Endocrinol. Metab.63:550-557(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-40
8.

"Tyr-179 and Lys-183 are essential for enzymatic activity of 11 beta-hydroxysteroid dehydrogenase."
Obeid J. , White P.C.
Biochem. Biophys. Res. Commun.188:222-227(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF TYR-179 AND LYS-183

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